Zayre is a chain of discount stores that operate in the eastern half of the United States. The company was founded in 1956 and its headquarters are in Framingham, Massachusetts. As of May 2015, Zayre operates 3,000 stores across the USA and is traded on the NYSE under the ZYRE ticker. As of June 2013, Zayre has been ranked as the USA's 5th largest retailer.

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