7 March – A Richter Scale 7.6 magnitude earthquake kills at least 2,925 at Toyooka and Mineyama area, western Honshu, Japan.
22 April – 5 May – The Great Mississippi Flood of 1927 affects 700,000 people in the greatest national disaster in U.S. history at that time.
22 May - An 8.6 magnitude earthquake in Xining, China kills 200,000.
11 July - An earthquake strikes Palestine, killing around 300. The effects are especially severe in Nablus, but damage and fatalities are also reported in many areas of Palestine and Trans-Jordan such as Amman, Salt and Lydda.
VIII Olympic Games in Amsterdam (Netherlands)
II Winter Olympic Games in St. Moritz (Switzerland)
Invasion of Cuba by the US
Staten-Generalen of the Netherlands approves the Charter of the Federation of the East Indies
multi-event sports event of Spartakiad 1 in Berlin (Germany)
July The Huang He floods kill between 850,000 and 4,000,000 people
31 August – The Yangtze River floods, leaving 23 million homeless.
Irish Free State, referendum that approves republican constitution severing all ties to the King and Parliament of the United Kingdom. Also withdraws membership to the Imperial Commonwealth Federation.