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- November 8 - In one of the most contentious presidential elections in modern U.S. history, incumbent Vice President Richard Nixon (R-CA) defeats U.S. Senator John F. Kennedy (D-MA) by a narrow margin in the popular vote and a much larger margin in the Electoral College.
- January 20 - Richard Nixon and Henry Cabot Lodge, Jr., are sworn in as the 35th President and 37th Vice President of the United States, respectively, at the east portico of the U.S. Capitol Building in Washington, D.C.
- January 21 - The United States Senate officially confirms Ralph Bunche as Secretary of Health, Education, and Welfare by a vote of __-__, making him the first African American to be appointed to a U.S. cabinet-level position.