Spithridates (374 BC - 317 BC) was satrap of Lydia and Ionia under Darius III. He is best know for killing Alexander, the leader of the Macedonian invasion of 334 BC, in the battle of the Granicus river. He also played a significant role in putting down the revolts throughout Asia Minor following the Macedonian invasion. Spithridates was assassinated by a Lydian spy while campaigning in Lydia. By the time of his death he had pacified most lands east of the Halys river.

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