First Ottoman-Venetian War
Part of Ottoman Wars in Europe
Date 1463 — 1466
Location Negroponte (Euboea), Morea, Aegean Sea, and minor clashes in Albania
Result Ottoman victory, Treaty of Smyrna
  • Cession of Negroponte to the Ottomans
  • Morea remains a Venetian protectorate
  • Reparations to the Ottomans through transfer of ships
Flag of the Ottoman Empire (1453-1517) Ottoman Empire Flag of Most Serene Republic of Venice Republic of Venice

Emblem of the Papacy SE Papal States
Maniots and Greek rebels

Commanders and leaders
Flag of the Ottoman Empire (1453-1517) Mehmed II
Flag of Most Serene Republic of Venice Sigismondo Malatesta

The First Ottoman-Venetian War (1463 - 1466) was a military and naval engagement fought between the Republic of Venice and her allies, and the Ottoman Empire, from 1463 to 1466. The war was fought years after the fall of the city of Constantinople and the ancient Byzantine Empire by the Ottomans, resulting in the loss of a few Venetian holdings in Greece and Albania.

The peace, signed at the port city of Smyrna, was a key factor in the initial victories in the later Ottoman-Italian Wars, as the agreements set by the Ottomans ensured non-aggression and the neutrality of Venice in future conflicts. The war also saw the rapid expansion of the Ottoman navy, and with the cession of numerous Venetian high-end vessels, brought a warning to the Venetians to beware of their holdings outside of Italy. This caution caused the Republic to seek alternative routes to the sea other than by the Adriatic Sea, worried the Ottomans may cut off their route at any moment.