The Cherokee tribe was located in what is now present-day Tennessee and North Carolina. The 1663 Charter granted Lords Proprietor title to all land from the southern border of the Virginia Colony to the present-day border of the US state of Georgia. The present-day cities of Wilmington and Charleston were founded but back then, their names were Clarendon (Wilmington) and Charles-Town (Charleston).
Conflict with the Natives
The Cherokee tribe was located in the eastern portion of Tennessee and the western portion of North Carolina. The Cherokee soon came into conflict with settlers, as they expanded westward, intruding upon the Cherokee's native and hunting lands. Skirmishes became common between settlers and the Cherokee, leading to the federal government in the United States mobilizing the North Carolina, Virginia, Georgia and South Carolina militia to destroy the natives. Under the command of General George Washington, a native Virginian, and after waiting two weeks, an army of about 5,000 soldiers began their march toward the Cherokee homeland in the Appalachian Mountains.
Course of the War
In July 15, 1767, the 5,000 man army began their march toward the Cherokee homeland. General George Washington divided his army into three separate groups, and sent them to surround the Cherokee main village. On July 18, after two days of waiting for a pre-offensive attack by the Cherokee, General Washington determined that the Cherokee don't know that the militia is around them, and on July 19, the army launched a three-pronged attack onto the central village of the Cherokee.
The devastating American attack went on later to be called the "Massacre at Appalachia", due to the army massacring nearly 105 women and children, among the 155 warriors that were intended to protect them. However, 55 scouts managed to escape the massacre that was occurring. Among the survivors was their leader, Attakullakulla, who assembled an army of 1,000 against the militia. Attakullakulla and his army marched back toward the massacre site, and began to prepare for an offensive against Washington's militia. Attakullakulla launched an offensive against Washington on July 19, and killed 155 soldiers. Eventually, Attakullakulla fell back into the forests, and prepared for another offensive.
Washington chased after Attakullakulla into the forests, and attacked the unprepared camp of Cherokee, killing Attakullakulla, and routing the remainder of the Cherokee back into Tennessee, by OTL Oak Ridge. The new chief of the Cherokee met with Washington on July 20, and agreed to an ceasefire. Upon the terms and conditions, the Cherokee will be forced to relocate on the other side of the Mississippi, and those who didn't were immediately deported on the western portion of the Mississippi.
The war opened up numerous territories for settlement, and led to the establishment of many eastern cities. This was consider the first of many wars between the Natives and the Americans. The Cherokee were severely depopulated by the war, the long trail across the continent to western North America and conflict with other natives.