Eight changes happen, all in the fifteenth century. This leads to a complete difference between this timeline and the OTL.
POD 1/1410: Teutonic Order defeat Poland, Lithuania and Russia at the Battle of Grunwald
POD 2/1415: Moors defeat Portugal at Cueta.
POD 3/1420: Joan of Arc dies after falling from a hill, aged eight.
POD 4/1437: Pacachuti murdered four months before founding the Inca Empire.
POD 5/1449: Aztec fishing trip lost in storm, discover Europe.
POD 6/1453: Byzantine Empire defeat Ottomans in the Siege of Constantinople, manage to survive.
POD 7/1475: Ottoman Empire defeat Moldavia at Battle of Vaslui.
POD 8/1494: France do not agree to help Milan against Venice.
1410: POD 1
1411: Teutonic Order begin to convert Russia to Roman Catholicism.
1415: POD 2
1416: Russia's official religion becomes Roman Catholicism.
1417: Russia form alliance with the Teutonic Order.
1418: Poland attack Braclaw in Lithuania, ending alliance.
1420: POD 3
1421: Lithuania declares war on Poland and Russia. Poland forms alliance with the Teutonic Order.
1422: Poland conquers South-eastern Lithuania.
1424: Moors invade Portugal.
1425: Russia conquers Western Lithuania.
1427: Lithuania forms alliance with Golden Horde; Russia surrenders.
1428: Russia, Lithuania and the Golden Horde merge to form the Golden Kingdom of the North.
1429: England take Orleans from France.
1430: Treaty of Novgorod: Teutonic Order disbands/ Poland take control of former Teutonic and Lithuanian land/ Russia gains independence but lose half of their former land.
1431: England take Bourges.
1435: England take Tours and Lyon.
1436: Treaty of Marseilles; end of the War of the Ninety-Nine Years.
1437: POD 4
1438: Chanka Tribes invade Kingdom of Cuzco. King Urco killed in the First Battle of Cuzco City.
1439: Cuzco Kingdom falls.
1440: Moors have control of Southern Portugal.
1441: Moors invade Castile. Castile and Portugal form alliance.
1446: Milan invade France from Monaco.
1448: Siege of Lyons; England and France form alliance against Milan.
1449: POD 5
1450: Aztec Fishing boat sets of from Lisbon to the "old world".
1452: Milan invade the Swiss Confederacy. Pull out of France.
1453: POD 6
1456: Byzantine Empire defeat Ottomans at Thessaloniki; retake Macedonia.
1458: Henry VI dies; Edward IV (ATL) becomes king aged just 5.
1459: Richard, Duke of York assaninates Edward IV; becomes king Richard III(ATL)
1461: Edmund Tudor claims the throne of England; start of the War of the Roses.
1462: Lithuania revolt against Poland.
1465: France retake much of former land while England is in turmoil.
1467: Battle of Vilnius; Lithuania regain independance.
1468: The Twelve Revolutions; France splinters into thirteen nation-states.
1470: Aztec army arrives in Lisbon; lays siege to the city.
1471: Edmund Tudor becomes King Edmund I of England; sets about defending country.
1472: The Duke of York flees to Scotland; prepares army.
1474: Byzantine Empire retakes all of Greece.
1475: POD 7
1476: Ottomans destroy Moldavia.
1478: Ottoman army marches into Russia, but are met by a larger Mongol army. There is much bloodshed.
1479: Ottomans launch full out attack against Mongols, but are in turn attacked by the Byzantines.
1480: France and England form alliance to defeat other French states.
1481: Most of Portugal conquered by Aztecs, as well as most Moorish lands in Iberia.
1484: Kingdom of Iberia formed by Castile, Aragon and Portugal.
1486: Byzantines take all of Turkey, while Ottomans are forced to surrender against Mongols.
1489: France have retook most of former land, with only Normandy, Brittany and Aquitane survive.
1491: Siege of Carlisle; start of Richard's invasion of England.
1492: Moors defeat Aztecs at Ceuta, ensure Morocco shall not be invaded by the Mesoamericans.