The Mayor of San Francisco, California is the head of the executive branch of the city and county government of San Francisco. This is a list of holders of the office of mayor since statehood.
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| 3 | Harris, Stephen RandallStephen Randall Harris | 01852-01-01 January 1, 1852 | 01852-11-09 November 9, 1852 | Democratic | |
| 4 | Brenham, Charles JamesCharles James Brenham | 01852-11-10 November 10, 1852 | 01853-10-02 October 2, 1853 | Whig | |
| 5 | Garrison, Cornelius KingslandCornelius Kingsland Garrison | 01853-10-03 October 3, 1853 | 01854-10-01 October 1, 1854 | Whig | |
| 6 | Webb, Stephen PalfreyStephen Palfrey Webb | 01854-10-02 October 2, 1854 | 01855-06-30 June 30, 1855 | Know Nothing | |
| 7 | Van Ness, JamesJames Van Ness | 01855-07-01 July 1, 1855 | 01856-07-07 July 7, 1856 | Democratic | |
| 8 | Whelan, George J.George J. Whelan | 01856-07-08 July 8, 1856 | 01856-11-14 November 14, 1856 | American | |
| 9 | Burr, Ephraim WillardEphraim Willard Burr | 01856-11-15 November 15, 1856 | 01859-10-02 October 2, 1859 | American | |
| 10 | Teschemacher, Henry F.Henry F. Teschemacher | 01859-10-03 October 3, 1859 | 01863-06-30 June 30, 1863 | Vigilance People's | |
| 11 | Coon, Henry PerrinHenry Perrin Coon | 01863-07-01 July 1, 1863 | 01867-12-01 December 1, 1867 | Vigilance People's | |
| 12 | McCoppin, FrankFrank McCoppin | 01867-12-02 December 2, 1867 | 01869-12-05 December 5, 1869 | Democratic | |
| 13 | Selby, Thomas HenryThomas Henry Selby | 01869-12-06 December 6, 1869 | 01871-12-03 December 3, 1871 | Republican | |
| 14 | Alvord, WilliamWilliam Alvord | 01871-12-04 December 4, 1871 | 01873-11-30 November 30, 1873 | Republican | |
| 15 | Otis, JamesJames Otis[a] | 01873-12-01 December 1, 1873 | 01875-10-30 October 30, 1875 | Populist | |
| 16 | Hewston, GeorgeGeorge Hewston[a] | 01875-11-04 November 4, 1875 | 01875-12-05 December 5, 1875 | Democratic | |
| 17 | Bryant, Andrew JacksonAndrew Jackson Bryant | 01875-12-06 December 6, 1875 | 01879-11-30 November 30, 1879 | Populist | |
| 18 | Kalloch, Isaac SmithIsaac Smith Kalloch | 01879-12-01 December 1, 1879 | 01881-12-04 December 4, 1881 | Democratic | |
| 19 | Blake, Maurice CareyMaurice Carey Blake | 01881-12-05 December 5, 1881 | 01883-01-07 January 7, 1883 | Republican | |
| 20 | Bartlett, WashingtonWashington Bartlett | 01883-01-08 January 8, 1883 | 01887-01-02 January 2, 1887 | Democratic | |
| 21 | Pond, Edward B.Edward B. Pond | 01887-01-03 January 3, 1887 | 01891-01-04 January 4, 1891 | Democratic | |
| 22 | Sanderson, George HenryGeorge Henry Sanderson | 01891-01-05 January 5, 1891 | 01893-01-03 January 3, 1893 | Republican | |
| 23 | Ellert, Levi RichardLevi Richard Ellert | 01893-01-03 January 3, 1893 | 01895-01-06 January 6, 1895 | Republican | |
| 24 | Sutro, AdolphAdolph Sutro | 01895-01-07 January 7, 1895 | 01897-01-03 January 3, 1897 | Populist | |
| 25 | Phelan, James D.James D. Phelan | 01897-01-04 January 4, 1897 | 01902-01-07 January 7, 1902 | Democratic | |
| 26 | Schmitz, EugeneEugene Schmitz[b] | 01902-01-08 January 8, 1902 | 01907-07-08 July 8, 1907 | Union Labor
[10] | |
| 27 | Boxton, CharlesCharles Boxton[b] | 01907-07-09 July 9, 1907 | 01907-07-16 July 16, 1907 | Union Labor | |
| 28 | Taylor, Edward RobesonEdward Robeson Taylor[b] | 01907-07-16 July 16, 1907 | 01910-01-07 January 7, 1910 | Democratic | |
| 29 | McCarthy, P. H.P. H. McCarthy | 01910-01-08 January 8, 1910 | 01912-01-07 January 7, 1912 | Union Labor | |
| 30 | Rolph, JamesJames Rolph[c] | 01912-01-08 January 8, 1912 | 01931-01-06 January 6, 1931 | Republican | |
| 31 | Rossi, Angelo JosephAngelo Joseph Rossi | 01931-01-07 January 7, 1931 | 01944-01-07 January 7, 1944 | Republican | |
| 32 | Lapham, RogerRoger Lapham | 01944-01-08 January 8, 1944 | 01948-01-07 January 7, 1948 | Republican | |
| 33 | Robinson, ElmerElmer Robinson | 01948-01-08 January 8, 1948 | 01956-01-07 January 7, 1956 | Republican | |
| 34 | Christopher, GeorgeGeorge Christopher | 01956-01-08 January 8, 1956 | 01964-01-07 January 7, 1964 | Republican | |
| 35 | Shelley, JohnJohn Shelley | 01964-01-08 January 8, 1964 | 01968-01-07 January 7, 1968 | Democratic | |
| 36 | Joseph Alioto | 01968-01-08 January 8, 1968 | 01976-01-07 January 7, 1976 | Democratic | |
| 37 | George Moscone | 01976-01-08 January 8, 1976 | 01978-11-27 January 7, 1984 | Democratic | |
| 38 | John Molinari | January 8, 1984 | January 7, 1988 | Democratic | |
| 39 | Art Agnos | January 8, 1988 | January 7, 1992 | Democratic | |
| 40 | Frank Jordan | January 8, 1992 | January 7, 1996 | Democratic | |
| 41 | Willie Brown | January 8, 1996 | January 7, 2004 | Democratic | |
| 42 | Tom Ammiano | January 8, 2004 | incumbent |